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DESONAP

Quick Overview

Our aim is to reach out to the globe within shortest possible time frame.  


To promote this objective, not only we distribute and market our Endocrinology  range of products globally through our distribution channels but we also undertake ‘contract manufacturing’& ‘formulation development ’of our wide range of generic products such as Desonap which contain  Desmopressin Acetate...0.01% w/v Eq. to Desmopressin BP....0.0089%w/v.


 


 

Desonap-60md NS

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Details

Composition:

Each ml contains:

Desmopressin Acetate...................................... 0.01% w/v

Eq. to Desmopressin BP...................................0.0089%w/v

Benzalkonium chloride Solution BP....................0.02% w/v

Excipients                                                         q.s.

Each Spray Delivers:

Desmopressin Acetate ................................. 10 mcg

Eq. to Desmopressin BP .............................  8.9 mcg

 

Description:

Desmopressin (as Desmopressin acetate) is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation.

Indications:

Central Cranial Diabetes Insipidus: Desonap Intranasal Spray is indicated as antidiuretic replacement therapy in the management of central cranial diabetes insipidus and for management of the temporary polyuria and polydipsia, following head trauma or surgery in the pituitary region. It is ineffective for the treatment of nephrogenic diabetes insipidus.

 Dosage and administration:

Central Cranial Diabetes Insipidus:

The usual dosage range in adults is 0.1 to 0.4 ml daily, either as a single dose or divided into two or three doses. Most adults require 0.2 ml daily in two divided doses. The morning and evening doses should be separately adjusted for an adequate diurnal rhythm of water turnover.

For children aged 3 months to 12 years, the usual dosage range is 0.05 to 0.3 ml daily, either as a single dose or divided into two doses.

Geriatric Use: This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.

 Contraindications:

 

Desonap Nasal Spray is contraindicated in individuals with syndrome of inappropriate ADH secretion (SIADH).

Desonap is contraindicated in patients with a history of known or suspected cardiac insufficiency and other conditions requiring treatment with diuretics.

 Presentation:

6 ml bottle with spray pump delivering 60 sprays of 10 mcg.

 
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